Mediterranean Diet & Psoriasis: 2025 MEDIPSO Study | Zerigo Health

Published in JAMA Dermatology · September 2025

Key Finding

What the Study Did

Researchers wanted to find out if eating a Mediterranean Diet could help people with mild to moderate psoriasis improve their skin symptoms. The study, published in JAMA Dermatology in September 2025, ran for 16 weeks and split 38 adult psoriasis patients into two groups — one followed the Mediterranean Diet with guidance from a dietitian, and the other followed basic low-fat dietary advice. At the end of the study, doctors measured how much each person's skin had improved.

Results at a Glance

• Nearly half (47%) of Mediterranean Diet participants achieved 75% clearer skin in just 16 weeks — compared to zero in the comparison group
• Skin severity scores dropped significantly in the Mediterranean Diet group, with no meaningful change in the comparison group
• Blood sugar levels improved — an important bonus, since people with psoriasis already face higher risk of heart disease and diabetes
• No medication changes were made — the only difference between the two groups was diet

“This study shows that what you eat can make a real difference in managing psoriasis. A simple, sustainable dietary change — with no side effects — produced meaningful skin improvement in nearly half of participants in just four months.”