psoriasis

The Mediterranean Diet & Psoriasis: 2025 MEDIPSO Study

A 2025 JAMA Dermatology study found 47% of psoriasis patients achieved 75% clearer skin in 16 weeks following a Mediterranean Diet. Read the findings.

ZerigoHealth

Published Mar 26, 2026 · 2 min read

Published in JAMA Dermatology · September 2025

Key Finding

Result	What it means
47%	of patients following a Mediterranean Diet achieved 75% clearer skin in just 16 weeks — compared to zero in the comparison group
0%	comparison group reached the same improvement
↓ A1c	blood sugar improved significantly in the Med Diet group
Rx ✓	no medication changes — diet alone was the only variable

What the Study Did

Researchers wanted to find out if eating a Mediterranean Diet could help people with mild to moderate psoriasis improve their skin symptoms. The study, published in JAMA Dermatology in September 2025, ran for 16 weeks and split 38 adult psoriasis patients into two groups — one followed the Mediterranean Diet with guidance from a dietitian, and the other followed basic low-fat dietary advice. At the end of the study, doctors measured how much each person's skin had improved.

Results at a Glance

Nearly half (47%) of Mediterranean Diet participants achieved 75% clearer skin in just 16 weeks — compared to zero in the comparison group
Skin severity scores dropped significantly in the Mediterranean Diet group, with no meaningful change in the comparison group
Blood sugar levels improved — an important bonus, since people with psoriasis already face higher risk of heart disease and diabetes
No medication changes were made — the only difference between the two groups was diet

“This study shows that what you eat can make a real difference in managing psoriasis. A simple, sustainable dietary change — with no side effects — produced meaningful skin improvement in nearly half of participants in just four months.”

Reference

Perez-Bootello, J., et al. (2025). Mediterranean Diet and Patients With Psoriasis: The MEDIPSO Randomized Clinical Trial. JAMA Dermatology, 161(12), 1215–1223. doi:10.1001/jamadermatol.2025.3410

This article is for general education, not medical advice. Check with your own doctor about your care.